In order to optimize the learner's acquisition of the various knowledge and concepts related to theories and applications. (General Chemistry), we propose several methods and activities: Teaching methods and activities between physical attendance at courses and exercises, and distance learning. 😉 A. Physical presence: We can summarize the importance and role of physical presence in five main points. 1) In courses, the principle of participation and dialogue is always present between teacher and learner, so we try to ensure that it is the learner himself who arrives at the idea and theory through a variety of teaching methods. 2) During the course, the learner takes some of the main points from each course, links them together and turns them into a summary of the course and a basis on which to build later. 3) In tutorials, the learner reflects on, proposes and solves various problems. 4) During and after the end of each course, it is the learner who reflects on, proposes and solves the various course problems and exercises. 5) In the laboratory, the learner's acquisition of knowledge is deepened through a variety of experiments. At the end of each course, we make sure that all the work is done by the learner him/herself, in the form of worksheets. B. Distance learning: The importance of making courses available on the Moodle platform can be summed up in three main points: 1) Putting each semester's courses in PDF and SCORM format will enable learners to organize their main ideas and the points they have learned by attending the courses, this pedagogical support is followed by teaching aids are followed by examples and videos to help the learners deepen their understanding through practical examples of the ideas presented. 2) At the end of each course, several exercises and self-evaluation questions are offered to students to reinforce the concepts presented. 3) A discussion area between teacher and learner to raise questions or problems related to course understanding, and to present the different ideas that the learner may have developed through the module.